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Professor of Psychiatry and Psychology
University of Pittsburgh School of Medicine
Western Psychiatric Institute and Clinic
Phone: 412-246-5550
Fax: 412-246-5530
Pamela Gaidosh Moot, 412-246-5522

Research Program
Under a MERIT Award grant from the National Institute of Mental Health, Dr. Frank found
Interpersonal and Social Rhythm Therapy, a psychotherapy she and her colleagues developed
for the treatment of bipolar disorder, was efficacious in the prevention of manic and depressive
recurrence. She is currently conducting a joint study with researchers at the University of Pisa,
Italy, aimed at deriving algorithms that will enable clinicians to determine whether a given
depressed patient should be treated with medication or psychotherapy.
Leadership Positions and Honors
American Psychiatric Association, (Honorary Fellow), 1991
National Institute of Mental Health MERIT Award, 1992-2002
National Depressive and Manic-Depressive Association Gerald L. Klerman Lifetime
Research Award, 1996
Stephen V. Logan Award of the National Alliance for the Mentally Ill for outstanding
contribution by a psychologist in understanding brain disorders, 1999
The 1999 Association for Clinical Psychosocial Research Gerald L. Klerman Award for
Mentorship, 1999
Member, Institute of Medicine, National Academy of Sciences, 1999
The Mental Health Association of Allegheny County, First Recipient of the Ellen Frank
Psychiatric Research Award, 2000

Representative Publications 
Frank E, Kupfer DJ, Perel JM, Cornes CL, Jarrett D, Mallinger A, Thase M, McEachran AB,
Grochocinski VJ:  Three year outcomes for maintenance therapies in recurrent depression.
Arch Gen Psychiatry 47:1093-1099, 1990.
Frank E, Kupfer DJ, Thase ME, Mallinger AG, Swartz H, Fagiolini AM, Grochocinski V,
Houck P, Scott J, Thompson W, Monk T:  Two year outcomes for interpersonal and social
rhythm therapy in individuals with bipolar I disorder.  Arch Gen Psychiatry 62:996-1004, 2005.
Frank E (Ed):  Treating Bipolar Disorder:  A Clinician’s Guide to Interpersonal and Social Rhythm
Therapy.  New York, The Guilford Press, 2005.
  Revised 5/16/2006  la/tc


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