| . |
 disorders.
The long-term goals of Dr. Hariri’s research program are to identify specific
genetically
moderated neurobiological pathways mediating variability in behavior and
risk for
neuropsychiatric
disease that will allow for the development of more effective, individually
tailored
disease
treatment and, ultimately, prevention.
Leadership Positions and Honors
 NARSAD
Bowman Family Investigator Award, 2003-2005
UPMC
Junior Faculty Scholar (NIH R25), 2003-2004
NIMH
Richard Wyatt Memorial Fellow, 2002-2003
NIH
Fellows Award for Research Excellence, 2002
Neuroimaging
Training Grant (NIH T32) Fellow, 1999-2000
ARCS
Foundation Scholar, 1997-1999
Representative Publications
Hariri
AR, Mattay VS, Tessitore A, Kolachana BS, Fera F, Goldman D, Egan MF,
 Weinberger
DR: Serotonin transporter genetic variation and the response of the human
amygdala.
Science
297:400-403, 2002.
Hariri
AR, Goldberg TE, Mattay VS, Kolachana BS, Callicott JH, Egan MF, Weinberger
DR:
Brain-derived
neurotrophic factor val66met polymorphism affects human memory-related
hippocampal
activity and predicts memory performance. J Neurosci 23:6690-6694, 2003.
Hariri,
A.R., Drabant, E.M., Munoz, K.E., Kolachana, B.S., Mattay, V.S., Egan,
M.F. &
Weinberger,
D.R. A susceptibility gene for affective disorders and the response of
the human
amygdala.
Arch Gen Psychiatry 62:146-152, 2005.
Pezawas
L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS,
Egan
MF, Mattay VS, Hariri AR, Weinberger DR: 5-HTTLPR polymorphism impact anatomy
and
function
of affective neural circuitry: A genetic mechanism for susceptibility to
depression and
anxiety
disorders. Nature Neurosci 8:828-834, 2005.
Brown
SM, Peet E, Manuck SB, Williamson DE, Dahl RE, Ferrell RE, Hariri AR: A
regulatory
variant
of the human tryptophan hydroxylase-2 gene biases amygdala reactivity.
Molec Psychiatry
10:884-888,
2005.
Hariri
AR, Holmes A: Genetics of emotional regulation: The role of the serotonin
transporter in
neural
function. Trends in Cognit Sci 10:182-191, 2006 |
