Member ~ PMBC External Advisory Board Norman Cousins Professor Cousins Center for Psychoneuroimmunology Semel Institute for Neuroscience and Human Behavior - David Geffen School of Medicine at UCLA Email: mirwin1@ucla.edu Phone: 310-825-8281Fax: 310-794-9247 Assistant: Cathey Heron, cheron@mednet.ucla.edu Research Program Working in the area of psychoneuroimmunology for nearly two decades, Dr. Irwin has authored more than 200 articles and chapters, as well as one book Human Psychoneuroimmunology. His research is broadly based on the interactions between behavior and immunity, with an emphasis on the consequences of major depression on immune processes relevant to infectious disease risk as well as inflammatory disorders.  More recently, Dr. Irwin and his colleagues has studied the immunologic and health consequences of insomnia, with evaluation of the reciprocal links between inflammatory cytokines and disordered sleep in clinical populations.  His present

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research program also includes investigations examining the capacity of mind-body interventions to improve insomnia with consequences for inflammatory mechanisms and viral specific immunity in older adults and in cancer survivors. Leadership Positions and Honors Norman Cousins Chair for Psychoneuroimmunology at the UCLA David Geffen School of Medicine, and is Director of the Cousins Center for Psychoneuroimmunology at the UCLA Semel Institute for Neuroscience and Human Behavior Professor of Psychology at UCLA, Director of the UCLA Training Program in Psychoneuroimmunology and Mental Health Chair of the UCLA Collaborative Centers for Integrative Medicine Member of the Advisory Board for the UCLA Center on Aging and for the UCLA Jonsson Comprehensive Cancer Center Past President, Psychoneuroimmunology Research Society and the Academy of Behavioral Medicine Research Fellow, American Psychiatric Association and the American College of Psychiatrists Associate Editor of Brain, Behavior, and Immunity Member of the Editorial Board of Psychosomatic Medicine Recipient of the 2005 Faculty Research Mentor Award from the Department of Psychiatry and Biobehavioral Science at the David Geffen School of Medicine, UCLA Past appoints on the NIMH Mental Health and AIDS Initial Review Group, and the Advisory Council to the National Center for Complementary and Alternative Medicine Representative Publications  Irwin MR, Wang M, Campomayor CO, Collado-Hidalgo A, Cole SW:  Sleep deprivation and activation of morning levels of cellular and genomic markers of inflammation.  Arch Intern Med 166:1-7, 2006. Irwin M, Cole JC, Nicassio PM:  Comparative meta-analysis of behavioral interventions for insomnia and their efficacy in adults and in older adults 55+ years  Health Psychol 25:3-14, 2006. Oxman MN, Levin MJ, Johnson GR, Schmader KE, Straus SE, Gelb LE, Arbeit RD, Simberkoff MS, Gershon AA, Davis LE, Weinberg A, Boardman KD, Williams HM, Zhang JH, Peduzzi PN, Beisel C, Morrison VA, Guatelli J, Brooks PA, Kauffman CA, Pachucki CT,. Neuzil KM, Betts RF, Wright PF, Griffin R, Brunell P, Soto NE, Marques AR, Keay SK, Goodman RP, Cotton DJ, Gnann JW, Loutit J, Holodniy M, Keitel WA, Crawford G, Yeh SS, Lobo Z, Toney JF, Greenberg RN, Keller PM, Harbecke R, Hayward AR, Irwin MR, Kyriakides TS, Chan CY, Chan ISF, Wang W, Annunziato P, Silber JL, and for the Shingles Prevention Study Group. Prevention of herpes zoster and postherpetic neuralgia in older adults with a live attenuated varicella-zoster virus vaccine: results of Veterans Administration Cooperative Study #403 - The Shingles Prevention Study. N Engl J Med 352:2271-2284, 2005.

Revised 10/2/2006  la/tc