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Evidence suggests that Natural Killer Cell Activity (NKCA) influences disease outcomes among
patients with lymphoproliferative cancers. Traumatic and stressful experiences are known to be
associated with reductions in NKCA over time, and a diagnosis of cancer is probably severe
enough to precipitate such immune changes in some individuals.  It follows that the trauma
associated with being diagnosed with cancer might independently contribute to poor cancer
outcomes in patients with lymphoproliferative cancers.  Written emotional expression of traumatic
experiences has been associated with various health and immune benefits in some studies.
However, written emotional expression interventions have not yet been tested in cancer
populations.  In addition, the psychological mechanism(s) through which written emotional
expression exert health and possible immune benefits are poorly understood.  We will evaluate
health and immune benefits of a written emotional expression intervention among lymphoproliferative
cancer patients, and attempt to better understand the salutary psychological changes associated
with written emotional expression.(PDF VERSION)(MS WORD VERSION)
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  12/6/2005  LA / tc

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