Assistant Professor of Psychiatry and Psychology Director, Program in Cognitive Affective Neuroscience (PICAN) University of Pittsburgh, School of Medicine Email: gsiegle@pitt.edu Phone: 412-586-9233 Fax: 412-246-5880 Assistant: Agnes Haggerty, 412-586-9246 Research Program Dr. Siegle’s work examines neural and physiological aspects of emotional information processing in healthy individuals and individuals with mood and anxiety disorders through behavioral, functional magnetic resonance imaging (fMRI), and peripheral physiological assessment, as well as computational neural network modeling. These data are used to inform understanding of mind-body interactions in mood and anxiety disorders as well as to improve psychosocial treatments, including predicting recovery in therapy, understanding neural mechanisms of recovery, and developing new neuroscience-derived behavioral treatments.

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Leadership Positions and Honors Co-Leader, Translational Research in Emotion, Neuroscience, and Development (TREND) group, WPIC Director of Affective Neuroscience for the Clinical Cognitive Neuroscience Laboratory, WPIC Director of Affective Neuroscience for the Biometrics Research Program, VA Pittsburgh Member, Executive Committee, Mood Disorders Treatment and Research Program, WPIC Representative for NIMH at the 10th Anniversary of the Office of Behavioral and Social Sciences Research, 2006 Sutton Lecturer, New York Psychiatric Institute, 2006 WPIC Junior Faculty Scholar, 2001-2002 Dorothy K. Fricke Award, Voted by Joint Doctoral Program faculty for the graduate student who made the most significant contribution to the program, 1996 Associate Member, Sigma Xi, The Scientific Research Society, 1991 National Merit Scholar, 1987 Representative Publications  Siegle GJ, Steinhauer SR, Thase ME, Stenger VA, Carter CS: Can’t shake that feeling: fMRI assessment of sustained amygdala activity in response to emotional information in depressed individuals.  Biol Psychiatry 51:693-707, 2002. Thayer JF, Siegle GJ: Neurovisceral integration in cardiac and emotional regulation. IEEE Eng Med Biol 21:24-29, 2002. Siegle GJ, Steinhauer SR, Carter CS, Ramel W, Thase ME: Do the seconds turn into hours? Relationships between sustained pupil dilation in response to emotional information and self-reported rumination. Cogn Ther Res 27:365-383, 2003. Siegle GJ, Moore P, Thase ME: Rumination: One construct, many features in healthy individuals, depressed individuals, and individuals with Lupus. Cogn Ther Res 28:645-668, 2004. Siegle GJ, Carter CS, Thase ME:  Use of fMRI to predict recovery from unipolar depression with cognitive behavior therapy. Am J Psychiatry 163:735-738, 2006.

Revised 7/24/2006  la/tc